Importance of Intraoperative Frozen Section Biopsy in Head and Neck Surgical Oncology

  • Rajat Bhende Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
  • Raj Nagarkar Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
  • Rajendra Dhondge Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
  • Ahmer Arif Shaikh Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
  • Priyadarshini Banerjee Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
  • Ruturaj Deshpande Department of Head and Neck Surgical Oncology, HCG Manavta Cancer Hospital, Nasik, India.
Keywords: Neck Surgical Oncology, Intraoperative, Frozen Section, Biopsy.

Abstract

Purpose: This particular study aimed to determine the importance of intraoperative frozen section pathology of head and neck cancers in order to examine the reliability of the frozen section. Frozen section biopsy technique often helps a rapid diagnosis of a mass during surgery, which in turn may help a surgeon to know the status of the margins of his resection before closing.

Objective: The study was done to achieve tumour free surgical margin after resection of oral squamous cell carcinoma (OSCC). The study also examines to determine positive margins and their relation to tumour size, grade, and stage of oral squamous cell carcinoma.

Method: This cross-sectional study was done in 179 patients with oral sqamous cell carcinoma.

Results: Overall, 179 patients who underwent surgery for oral cavity cancers were included; 116 (65.2%) were males. The mean (+standard deviation) age of the included participants was 57.4 + 16.1 years. The most common tumour subsite was the tongue (n ¼ 71, 39.2%). The frozen, negative intraoperative malignancy and the postoperative safe surgical margin did not significantly differ.

Conclusion: The intra-operative frozen section biopsy plays an important role in Achieve tumour free surgical margin in the resection of oral squamous cell carcinoma. In this study, it was also noted that the number of positive margins increased in relation to increased tumour size and tumour stage (cTNM).

Published
2021-01-17